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epub Immune Deficiency and Cancer: Epstein-Barr Virus and Lymphoproliferative Malignancies download

by David T. Purtilo

  • ISBN: 030641662X
  • Author: David T. Purtilo
  • ePub ver: 1757 kb
  • Fb2 ver: 1757 kb
  • Rating: 4.2 of 5
  • Language: English
  • Pages: 488
  • Publisher: Springer; 1 edition (June 1, 1984)
  • Formats: mobi lrf lit lrf
  • Category: Other
  • Subcategory: Medicine & Health Sciences
epub Immune Deficiency and Cancer: Epstein-Barr Virus and Lymphoproliferative Malignancies download

Infectious Mononucleosis and Complications.

Infectious Mononucleosis and Complications. Responses to Epstein-Barr Virus in Immune Deficient Patients. Immunodeficiency to Epstein-Barr Virus in Chediak-Higashi Syndrome.

B cells, T cells, NK cells, and c cells, are infected with the Epstein–Barr virus (EBV).

Virus and Lymphoproliferative Malignancies" – электронная кніга аўтараў David T. Purtilo. for continuing generation of information regarding the mechanisms of induction of diseases by Epstein-Barr virus.

Immune Deficiency and Cancer: Epstein-Barr Virus and Lymphoproliferative Malignancies" – электронная кніга аўтараў David T. The discoveries of Burkitt, Epstein, and Henle have laid the foundation for continuing generation of information regarding the mechanisms of induction of diseases by Epstein-Barr virus. The discovery of the virus two decades ago resulted from clinical and basic science collaborative studies on Burkitt lymphoma.

Immune Deficiency and Cancer : Epstein-Barr Virus and Lymphoproliferative Malignancies.

Some occur as rare accidents of virus persistence in the B lymphoid system, while others arise as a result of viral entry into unnatural target cells.

Primary infection by EBV normally provokes potent immune responses which efficiently cope with the B-cell . cle{ionTE, title {Introduction to Epstein-Barr virus and lymphoproliferative diseases in immunodeficient individuals

Primary infection by EBV normally provokes potent immune responses which efficiently cope with the B-cell proliferation and provide lifelong latency (6). Persons with inherited or acquired immune defects, depending on the type and degree of the deficiency, are more or less vulnerable to life-threatening B-cell proliferation. cle{ionTE, title {Introduction to Epstein-Barr virus and lymphoproliferative diseases in immunodeficient individuals. 4209 } }. David T. Purtilo, George M. Klein.

Immune deficiency andcancer. Immune deficiency andcancer. 1 2 3 4 5. Want to Read. Are you sure you want to remove Immune deficiency andcancer from your list? Immune deficiency andcancer. Epstein-Barr virus and lymphoproliferative malignancies. by Purtilo, David T. Published 1984 by Plenum in New York, London.

Prevention of EBV-associated lymphoproliferative diseases in immune deficient individuals is preferred; however, standard therapy for the B cell lymphomas has been successful. Chemotherapy must be given cautiously lest further immune compromise result in opportunistic infections. Recently, Acyclovir has decreased morbidity of patients with acute infectious mononucleosis in immune competent persons.

Author: Dr Selene Ting, Medical Registrar, Middlemore Hospital, Auckland, New Zealand.

Authoritative facts about the skin from DermNet New Zealand. Author: Dr Selene Ting, Medical Registrar, Middlemore Hospital, Auckland, New Zealand.

The Epstein-Barr virus (EBV) is one of the most common human viruses, infecting more than 90% of the world's adult population. In some individuals the interplay between EBV replication, latency and immune control can be disrupted and evokes prolonged proliferation of EBV-infected lymphocytes and their malignant transformation. Since its discovery as the first human tumor virus, EBV has been implicated in the development of a wide range of human cancers.

The discoveries of Burkitt, Epstein, and Henle have laid the foundation for continuing generation of information regarding the mechanisms of induction of diseases by Epstein-Barr virus. The discovery of the virus two decades ago resulted from clinical and basic science collaborative studies on Burkitt lymphoma. Subse­ quently, nasopharyngeal carcinoma and infectious mononucleosis have been linked etiologically with the virus. During the first decade of research following the discovery of the virus, the mechanisms for the induction of BL, NPC, and IM were sought. At that time one prevailing view was that individual oncogenic strains of EBV were responsible for the different disorders. Paralleling the development of immunology in the 1970's was the accrual of knowledge about immunological events occurring during IM. These studies suggest that immune defense mechanisms deter­ mine the outcome of this viral infection rather than different viral strains. During the early 1970's, Starzl and Penn and Gatti and Good had noted an increased frequency of malignancy in renal allograft recipients and children with primary immune deficiency disorders, respectively. These observations provoked investigators to restudy the role of immune surveillance against malignancy. At that time immune surveillance was thought to occur against tumor-specific antigens; thereby neoplasms were eliminated.

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